4edv

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==The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese==
==The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese==
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<StructureSection load='4edv' size='340' side='right' caption='[[4edv]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
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<StructureSection load='4edv' size='340' side='right'caption='[[4edv]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4edv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EDV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4edv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EDV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0O2:GUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)+3-(TRIHYDROGEN+DIPHOSPHATE)'>0O2</scene>, <scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0O2:GUANOSINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)+3-(TRIHYDROGEN+DIPHOSPHATE)'>0O2</scene>, <scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e2k|4e2k]], [[4ee1|4ee1]], [[4edz|4edz]], [[4edy|4edy]], [[4edt|4edt]], [[4edr|4edr]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4edv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edv OCA], [https://pdbe.org/4edv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4edv RCSB], [https://www.ebi.ac.uk/pdbsum/4edv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4edv ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnaG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4edv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4edv OCA], [http://pdbe.org/4edv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4edv RCSB], [http://www.ebi.ac.uk/pdbsum/4edv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4edv ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PRIM_STAAU PRIM_STAAU]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.
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[[https://www.uniprot.org/uniprot/DNAG_STAAU DNAG_STAAU]] RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.[HAMAP-Rule:MF_00974]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Berger, J M]]
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[[Category: Large Structures]]
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[[Category: Chu, C]]
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[[Category: Staphylococcus aureus]]
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[[Category: Corn, J E]]
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[[Category: Berger JM]]
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[[Category: Rymer, R U]]
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[[Category: Chu C]]
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[[Category: Solorio, F A]]
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[[Category: Corn JE]]
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[[Category: Wang, J D]]
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[[Category: Rymer RU]]
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[[Category: Bacterial]]
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[[Category: Solorio FA]]
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[[Category: Catalytic domain]]
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[[Category: Wang JD]]
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[[Category: Nucleoside polyphosphate]]
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[[Category: Nucleoside triphosphate]]
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[[Category: Nucleotide]]
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[[Category: Protein-ligand complex]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Revision as of 07:06, 28 September 2022

The structure of the S. aureus DnaG RNA Polymerase Domain bound to pppGpp and Manganese

PDB ID 4edv

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