This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4ks5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid==
==Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid==
-
<StructureSection load='4ks5' size='340' side='right' caption='[[4ks5]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
+
<StructureSection load='4ks5' size='340' side='right'caption='[[4ks5]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4ks5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/I63a3 I63a3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KS5 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4ks5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/duck/Ukraine/1/1963(H3N8)) Influenza A virus (A/duck/Ukraine/1/1963(H3N8))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KS5 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1SO:(3S,4R,5R)-4-(ACETYLAMINO)-3-[4-(2-HYDROXYPROPAN-2-YL)-1H-1,2,3-TRIAZOL-1-YL]-5-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>1SO</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1SO:(3S,4R,5R)-4-(ACETYLAMINO)-3-[4-(2-HYDROXYPROPAN-2-YL)-1H-1,2,3-TRIAZOL-1-YL]-5-(PENTAN-3-YLOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>1SO</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ks1|4ks1]], [[4ks2|4ks2]], [[4ks3|4ks3]], [[4ks4|4ks4]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ks5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ks5 OCA], [https://pdbe.org/4ks5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ks5 RCSB], [https://www.ebi.ac.uk/pdbsum/4ks5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ks5 ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=385580 I63A3])</td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ks5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ks5 OCA], [http://pdbe.org/4ks5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ks5 RCSB], [http://www.ebi.ac.uk/pdbsum/4ks5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ks5 ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q0A480_I63A3 Q0A480_I63A3]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 20:
==See Also==
==See Also==
-
*[[Neuraminidase|Neuraminidase]]
+
*[[Neuraminidase 3D structures|Neuraminidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: I63a3]]
+
[[Category: Large Structures]]
-
[[Category: Kerry, P S]]
+
[[Category: Kerry PS]]
-
[[Category: Russell, R J.M]]
+
[[Category: Russell RJM]]
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Sialidase]]
+

Revision as of 09:10, 7 December 2022

Influenza neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-[4-(2-hydroxypropan-2-yl)-1H-1,2,3-triazol-1-yl]-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid

PDB ID 4ks5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools