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3re4

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==Crystal Structure of Archaeoglobus Fulgidus Rio1 Kinase bound to Toyocamycin.==
==Crystal Structure of Archaeoglobus Fulgidus Rio1 Kinase bound to Toyocamycin.==
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<StructureSection load='3re4' size='340' side='right' caption='[[3re4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='3re4' size='340' side='right'caption='[[3re4]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3re4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RE4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3re4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arcfl Arcfl]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RE4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TO1:4-AMINO-7-(BETA-D-RIBOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE'>TO1</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TO1:4-AMINO-7-(BETA-D-RIBOFURANOSYL)-7H-PYRROLO[2,3-D]PYRIMIDINE-5-CARBONITRILE'>TO1</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1zp9|1zp9]], [[1ztf|1ztf]], [[1zth|1zth]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1zp9|1zp9]], [[1ztf|1ztf]], [[1zth|1zth]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rio1, AF_1804 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2234 ARCFL])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rio1, AF_1804 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2234 ARCFL])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3re4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3re4 OCA], [http://pdbe.org/3re4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3re4 RCSB], [http://www.ebi.ac.uk/pdbsum/3re4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3re4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3re4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3re4 OCA], [https://pdbe.org/3re4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3re4 RCSB], [https://www.ebi.ac.uk/pdbsum/3re4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3re4 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RIO1_ARCFU RIO1_ARCFU]] Autophosphorylation of the rio1 protein is not necessary for maintenance of kinase activity. Prefers ATP over GTP. The yeast ortholog is involved in ribosome biogenesis.
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[[https://www.uniprot.org/uniprot/RIO1_ARCFU RIO1_ARCFU]] Autophosphorylation of the rio1 protein is not necessary for maintenance of kinase activity. Prefers ATP over GTP. The yeast ortholog is involved in ribosome biogenesis.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Arcfl]]
[[Category: Arcfl]]
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[[Category: Large Structures]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Kiburu, I N]]
[[Category: Kiburu, I N]]

Revision as of 05:59, 15 June 2022

Crystal Structure of Archaeoglobus Fulgidus Rio1 Kinase bound to Toyocamycin.

PDB ID 3re4

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