3vab

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==Crystal structure of Diaminopimelate decarboxylase from Brucella melitensis bound to PLP==
==Crystal structure of Diaminopimelate decarboxylase from Brucella melitensis bound to PLP==
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<StructureSection load='3vab' size='340' side='right' caption='[[3vab]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='3vab' size='340' side='right'caption='[[3vab]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vab]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brume Brume]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VAB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vab]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brume Brume]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VAB FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BMEI0084, lysA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224914 BRUME])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BMEI0084, lysA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224914 BRUME])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Diaminopimelate_decarboxylase Diaminopimelate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.20 4.1.1.20] </span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Diaminopimelate_decarboxylase Diaminopimelate decarboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.20 4.1.1.20] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vab OCA], [http://pdbe.org/3vab PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vab RCSB], [http://www.ebi.ac.uk/pdbsum/3vab PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vab ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vab OCA], [https://pdbe.org/3vab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vab RCSB], [https://www.ebi.ac.uk/pdbsum/3vab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vab ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q8YJJ9_BRUME Q8YJJ9_BRUME]] Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine (By similarity).[HAMAP-Rule:MF_02120]
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[[https://www.uniprot.org/uniprot/Q8YJJ9_BRUME Q8YJJ9_BRUME]] Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine (By similarity).[HAMAP-Rule:MF_02120]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Brume]]
[[Category: Brume]]
[[Category: Diaminopimelate decarboxylase]]
[[Category: Diaminopimelate decarboxylase]]
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[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: 6-diaminoheptanedioate carboxy-lyase]]
[[Category: 6-diaminoheptanedioate carboxy-lyase]]

Revision as of 18:35, 27 July 2022

Crystal structure of Diaminopimelate decarboxylase from Brucella melitensis bound to PLP

PDB ID 3vab

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