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3otc
From Proteopedia
(Difference between revisions)
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==Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II== | ==Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II== | ||
| - | <StructureSection load='3otc' size='340' side='right' caption='[[3otc]], [[Resolution|resolution]] 3.01Å' scene=''> | + | <StructureSection load='3otc' size='340' side='right'caption='[[3otc]], [[Resolution|resolution]] 3.01Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3otc]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3otc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTC FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3otb|3otb]], [[3otd|3otd]], [[3ote|3ote]]</td></tr> | + | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3otb|3otb]], [[3otd|3otd]], [[3ote|3ote]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ICF45, THG1L ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ICF45, THG1L ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3otc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3otc OCA], [https://pdbe.org/3otc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3otc RCSB], [https://www.ebi.ac.uk/pdbsum/3otc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3otc ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN]] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Doublie, S]] | [[Category: Doublie, S]] | ||
[[Category: Eckenroth, B E]] | [[Category: Eckenroth, B E]] | ||
Revision as of 10:56, 18 May 2022
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- Native II
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