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4mzg

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Current revision (10:22, 28 December 2022) (edit) (undo)
 
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==Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide==
==Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide==
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<StructureSection load='4mzg' size='340' side='right' caption='[[4mzg]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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<StructureSection load='4mzg' size='340' side='right'caption='[[4mzg]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4mzg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MZG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4mzg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MZG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MZG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mzg OCA], [https://pdbe.org/4mzg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mzg RCSB], [https://www.ebi.ac.uk/pdbsum/4mzg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mzg ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4mzf|4mzf]], [[4mzh|4mzh]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPIN1, OCR, SPIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mzg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mzg OCA], [http://pdbe.org/4mzg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mzg RCSB], [http://www.ebi.ac.uk/pdbsum/4mzg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mzg ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPIN1_HUMAN SPIN1_HUMAN]] May play a role in cell-cycle regulation during the transition from gamete to embryo (By similarity).
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[https://www.uniprot.org/uniprot/H32_HUMAN H32_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4mzg" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4mzg" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Spindlin|Spindlin]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Ding, X]]
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[[Category: Large Structures]]
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[[Category: Li, H]]
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[[Category: Ding X]]
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[[Category: Su, X]]
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[[Category: Li H]]
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[[Category: Gene regulation]]
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[[Category: Su X]]
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[[Category: Histone h3]]
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[[Category: Nuclear]]
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[[Category: Wnt signal]]
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Current revision

Crystal structure of human Spindlin1 bound to histone H3K4me3 peptide

PDB ID 4mzg

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