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4h67
From Proteopedia
(Difference between revisions)
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==Crystal structure of HMP synthase Thi5 from S. cerevisiae== | ==Crystal structure of HMP synthase Thi5 from S. cerevisiae== | ||
| - | <StructureSection load='4h67' size='340' side='right' caption='[[4h67]], [[Resolution|resolution]] 2.70Å' scene=''> | + | <StructureSection load='4h67' size='340' side='right'caption='[[4h67]], [[Resolution|resolution]] 2.70Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4h67]] is a 8 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4h67]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H67 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H67 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h67 OCA], [https://pdbe.org/4h67 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h67 RCSB], [https://www.ebi.ac.uk/pdbsum/4h67 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h67 ProSAT]</span></td></tr> | |
| - | + | ||
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/THI5_YEAST THI5_YEAST] Proposed biosynthetic enzyme involved in pyrimidine biosynthesis pathway above the hydroxymethyl-pyrimidine precursor leading to the thiamine moiety.<ref>PMID:12777485</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Coquille | + | [[Category: Saccharomyces cerevisiae]] |
| - | [[Category: Fitzpatrick | + | [[Category: Coquille SC]] |
| - | [[Category: Roux | + | [[Category: Fitzpatrick T]] |
| - | [[Category: Thore | + | [[Category: Roux C]] |
| - | + | [[Category: Thore S]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Revision as of 08:01, 3 November 2022
Crystal structure of HMP synthase Thi5 from S. cerevisiae
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