4p58

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==Crystal structure of mouse comt bound to an inhibitor==
==Crystal structure of mouse comt bound to an inhibitor==
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<StructureSection load='4p58' size='340' side='right' caption='[[4p58]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
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<StructureSection load='4p58' size='340' side='right'caption='[[4p58]], [[Resolution|resolution]] 2.06&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4p58]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P58 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P58 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4p58]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P58 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4P58 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2F6:1,3-DIMETHYL-1H,1H-3,4-BIPYRAZOLE'>2F6</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2F6:1,3-DIMETHYL-1H,1H-3,4-BIPYRAZOLE'>2F6</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Comt, Comt1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_O-methyltransferase Catechol O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.6 2.1.1.6] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Catechol_O-methyltransferase Catechol O-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.6 2.1.1.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p58 OCA], [http://pdbe.org/4p58 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p58 RCSB], [http://www.ebi.ac.uk/pdbsum/4p58 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p58 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4p58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p58 OCA], [http://pdbe.org/4p58 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4p58 RCSB], [http://www.ebi.ac.uk/pdbsum/4p58 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4p58 ProSAT]</span></td></tr>
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</StructureSection>
</StructureSection>
[[Category: Catechol O-methyltransferase]]
[[Category: Catechol O-methyltransferase]]
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[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
[[Category: Lanier, M]]
[[Category: Lanier, M]]
[[Category: Sam binding site]]
[[Category: Sam binding site]]
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[[Category: Transferase-transferase inhibitor complex]]

Revision as of 08:03, 17 April 2019

Crystal structure of mouse comt bound to an inhibitor

PDB ID 4p58

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