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4gwk

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==Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid==
==Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid==
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<StructureSection load='4gwk' size='340' side='right' caption='[[4gwk]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
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<StructureSection load='4gwk' size='340' side='right'caption='[[4gwk]], [[Resolution|resolution]] 1.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gwk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GWK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gwk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GWK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jkv|2jkv]], [[4gwg|4gwg]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwk OCA], [https://pdbe.org/4gwk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gwk RCSB], [https://www.ebi.ac.uk/pdbsum/4gwk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwk ProSAT]</span></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PGD, PGDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphogluconate_dehydrogenase_(NADP(+)-dependent,_decarboxylating) Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.44 1.1.1.44] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gwk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwk OCA], [http://pdbe.org/4gwk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gwk RCSB], [http://www.ebi.ac.uk/pdbsum/4gwk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwk ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN]] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
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[https://www.uniprot.org/uniprot/6PGD_HUMAN 6PGD_HUMAN] Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[6-phosphogluconate dehydrogenase|6-phosphogluconate dehydrogenase]]
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*[[6-phosphogluconate dehydrogenase 3D structures|6-phosphogluconate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: He, C]]
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[[Category: Large Structures]]
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[[Category: Zhang, L]]
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[[Category: He C]]
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[[Category: Zhou, L]]
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[[Category: Zhang L]]
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[[Category: 3-phosphoglycerate]]
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[[Category: Zhou L]]
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[[Category: 6-phosphogluconate dehydrogenase]]
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[[Category: Dehydrogenase]]
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[[Category: Nadp]]
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[[Category: Oxidoreductase]]
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Revision as of 07:23, 26 October 2022

Crystal structure of 6-phosphogluconate dehydrogenase complexed with 3-phosphoglyceric acid

PDB ID 4gwk

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