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4gcn

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==N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans==
==N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans==
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<StructureSection load='4gcn' size='340' side='right' caption='[[4gcn]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='4gcn' size='340' side='right'caption='[[4gcn]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4gcn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GCN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4gcn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CELE_R09E12.3, sti-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcn OCA], [https://pdbe.org/4gcn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gcn RCSB], [https://www.ebi.ac.uk/pdbsum/4gcn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcn ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gcn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcn OCA], [http://pdbe.org/4gcn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gcn RCSB], [http://www.ebi.ac.uk/pdbsum/4gcn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcn ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/STIP1_CAEEL STIP1_CAEEL]] Plays a role in gonad development. Up-regulates longevity and thermotolerance. Binds daf-21/hsp90 and inhibits its ATPase activity.<ref>PMID:19467242</ref> <ref>PMID:19559711</ref>
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[https://www.uniprot.org/uniprot/STIP1_CAEEL STIP1_CAEEL] Plays a role in gonad development. Up-regulates longevity and thermotolerance. Binds daf-21/hsp90 and inhibits its ATPase activity.<ref>PMID:19467242</ref> <ref>PMID:19559711</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caeel]]
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[[Category: Caenorhabditis elegans]]
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[[Category: Bigelow, L]]
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[[Category: Large Structures]]
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[[Category: Gu, M]]
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[[Category: Bigelow L]]
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[[Category: Joachimiak, A]]
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[[Category: Gu M]]
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[[Category: Structural genomic]]
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[[Category: Joachimiak A]]
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[[Category: Morimoto, R I]]
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[[Category: Morimoto RI]]
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[[Category: Oosten-Hawle, P Van]]
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[[Category: Osipiuk J]]
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[[Category: Osipiuk, J]]
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[[Category: Van Oosten-Hawle P]]
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[[Category: Co-chaperone]]
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[[Category: Hop]]
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[[Category: Hsp70]]
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[[Category: Hsp70/hsp90-organising protein]]
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[[Category: Hsp90]]
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[[Category: Mcsg]]
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[[Category: Protein binding]]
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[[Category: Psi-biology]]
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[[Category: Tetratricopeptide repeat domain]]
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[[Category: Tpr domain]]
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Revision as of 06:48, 26 October 2022

N-terminal domain of stress-induced protein-1 (STI-1) from C.elegans

PDB ID 4gcn

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