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4f3v

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==Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis==
==Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis==
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<StructureSection load='4f3v' size='340' side='right' caption='[[4f3v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='4f3v' size='340' side='right'caption='[[4f3v]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4f3v]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4F3V FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4f3v]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F3V FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SM:SAMARIUM+(III)+ION'>SM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">eccA1, MT3981, MTV027.03, Rv3868 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f3v OCA], [https://pdbe.org/4f3v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f3v RCSB], [https://www.ebi.ac.uk/pdbsum/4f3v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f3v ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4f3v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f3v OCA], [http://pdbe.org/4f3v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4f3v RCSB], [http://www.ebi.ac.uk/pdbsum/4f3v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4f3v ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ECCA1_MYCTU ECCA1_MYCTU]] Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10). Shows ATPase activity. Could provide energy for export of ESX-1 substrates.<ref>PMID:18974091</ref> <ref>PMID:16368961</ref>
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[https://www.uniprot.org/uniprot/ECCA1_MYCTU ECCA1_MYCTU] Probably part of a complex that is involved in secretion of ESX-1 substrates, such as EsxA (ESAT-6) and EsxB (CFP-10). Shows ATPase activity. Could provide energy for export of ESX-1 substrates.<ref>PMID:18974091</ref> <ref>PMID:16368961</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Evans, T J]]
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[[Category: Large Structures]]
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[[Category: Korotkov, K V]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Atpase]]
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[[Category: Evans TJ]]
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[[Category: Protein secretion]]
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[[Category: Korotkov KV]]
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[[Category: Protein transport]]
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[[Category: Tetratricopeptide repeat]]
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[[Category: Tpr domain]]
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Revision as of 04:32, 7 October 2022

Crystal structure of N-terminal domain of EccA1 ATPase from ESX-1 secretion system of Mycobacterium tuberculosis

PDB ID 4f3v

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