4j07

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==Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae==
==Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae==
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<StructureSection load='4j07' size='340' side='right' caption='[[4j07]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='4j07' size='340' side='right'caption='[[4j07]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4j07]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Myclb Myclb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J07 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4J07 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4j07]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_leprae_Br4923 Mycobacterium leprae Br4923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J07 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J07 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MLBr00560, ribH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=561304 MYCLB])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j07 OCA], [https://pdbe.org/4j07 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j07 RCSB], [https://www.ebi.ac.uk/pdbsum/4j07 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j07 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/6,7-dimethyl-8-ribityllumazine_synthase 6,7-dimethyl-8-ribityllumazine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.78 2.5.1.78] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4j07 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j07 OCA], [http://pdbe.org/4j07 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4j07 RCSB], [http://www.ebi.ac.uk/pdbsum/4j07 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4j07 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/RISB_MYCLB RISB_MYCLB]] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.[HAMAP-Rule:MF_00178]
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[https://www.uniprot.org/uniprot/RISB_MYCLB RISB_MYCLB] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.[HAMAP-Rule:MF_00178]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 6,7-dimethyl-8-ribityllumazine synthase]]
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[[Category: Large Structures]]
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[[Category: Myclb]]
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[[Category: Mycobacterium leprae Br4923]]
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[[Category: Structural genomic]]
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[[Category: 7-dimethyl-8-ribityllumazine synthase]]
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[[Category: Dmrl synthase]]
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[[Category: Lumazine synthase]]
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[[Category: Mycobacterium leprae]]
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[[Category: Ssgcid]]
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[[Category: Transferase]]
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Revision as of 21:22, 16 November 2022

Crystal structure of a PROBABLE RIBOFLAVIN SYNTHASE, BETA CHAIN RIBH (6,7-dimethyl-8-ribityllumazine synthase, DMRL synthase, Lumazine synthase) from Mycobacterium leprae

PDB ID 4j07

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