3b0i

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==Crystal structure of recombinant human alpha lactalbumin==
==Crystal structure of recombinant human alpha lactalbumin==
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<StructureSection load='3b0i' size='340' side='right' caption='[[3b0i]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='3b0i' size='340' side='right'caption='[[3b0i]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3b0i]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0I OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3B0I FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3b0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3B0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3B0I FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3b0k|3b0k]], [[3b0o|3b0o]]</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3b0k|3b0k]], [[3b0o|3b0o]]</div></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LALBA, LYZL7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">LALBA, LYZL7 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b0i OCA], [http://pdbe.org/3b0i PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3b0i RCSB], [http://www.ebi.ac.uk/pdbsum/3b0i PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3b0i ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3b0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b0i OCA], [https://pdbe.org/3b0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3b0i RCSB], [https://www.ebi.ac.uk/pdbsum/3b0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3b0i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LALBA_HUMAN LALBA_HUMAN]] Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
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[[https://www.uniprot.org/uniprot/LALBA_HUMAN LALBA_HUMAN]] Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Alpha-lactalbumin|Alpha-lactalbumin]]
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*[[Alpha-lactalbumin 3D structures|Alpha-lactalbumin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Makabe, K]]
[[Category: Makabe, K]]
[[Category: Calcium binding protein]]
[[Category: Calcium binding protein]]
[[Category: Glycoprotein]]
[[Category: Glycoprotein]]
[[Category: Metal binding protein]]
[[Category: Metal binding protein]]

Revision as of 11:19, 5 January 2022

Crystal structure of recombinant human alpha lactalbumin

PDB ID 3b0i

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