1m7b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1m7b.jpg|left|200px]]
[[Image:1m7b.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1m7b |SIZE=350|CAPTION= <scene name='initialview01'>1m7b</scene>, resolution 2.00&Aring;
+
The line below this paragraph, containing "STRUCTURE_1m7b", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=GTP:GUANOSINE-5&#39;-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= Rnd3 (amino acids 19-200) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1m7b| PDB=1m7b | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m7b OCA], [http://www.ebi.ac.uk/pdbsum/1m7b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1m7b RCSB]</span>
+
-
}}
+
'''Crystal structure of Rnd3/RhoE: functional implications'''
'''Crystal structure of Rnd3/RhoE: functional implications'''
Line 30: Line 27:
[[Category: Stege, P.]]
[[Category: Stege, P.]]
[[Category: Vetter, I R.]]
[[Category: Vetter, I R.]]
-
[[Category: small gtpase]]
+
[[Category: Small gtpase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 00:43:30 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:12:20 2008''
+

Revision as of 21:43, 2 May 2008

Image:1m7b.jpg

Template:STRUCTURE 1m7b

Crystal structure of Rnd3/RhoE: functional implications


Overview

The Rnd proteins constitute an exceptional subfamily within the Rho GTPase family. They possess extended chains at both termini and four prominent amino acid deviations causing GTPase deficiency. Herein, we report the crystal structure of the Rnd3/RhoE G-domain (amino acids 19-200) at 2.0 A resolution. This is the first GTP-structure of a Rho family member which reveals a similar fold but striking differences from RhoA concerning (i) GTPase center, (ii) charge distribution at several surface areas, (iii) C3-transferase binding site and (iv) interacting interfaces towards RhoA regulators and effectors.

About this Structure

1M7B is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystal structure of Rnd3/RhoE: functional implications., Fiegen D, Blumenstein L, Stege P, Vetter IR, Ahmadian MR, FEBS Lett. 2002 Aug 14;525(1-3):100-4. PMID:12163169 Page seeded by OCA on Sat May 3 00:43:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1m7b"
Personal tools