This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4tuh
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4tuh' size='340' side='right' caption='[[4tuh]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='4tuh' size='340' side='right' caption='[[4tuh]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4tuh]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TUH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4tuh]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TUH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TUH FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=38H:2-[8-(1,3-BENZOTHIAZOL-2-YLCARBAMOYL)-3,4-DIHYDROISOQUINOLIN-2(1H)-YL]-5-{3-[4-(1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL)PHENOXY]PROPYL}-1,3-THIAZOLE-4-CARBOXYLIC+ACID'>38H</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=38H:2-[8-(1,3-BENZOTHIAZOL-2-YLCARBAMOYL)-3,4-DIHYDROISOQUINOLIN-2(1H)-YL]-5-{3-[4-(1H-PYRAZOLO[3,4-D]PYRIMIDIN-1-YL)PHENOXY]PROPYL}-1,3-THIAZOLE-4-CARBOXYLIC+ACID'>38H</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BCL2L1, BCL2L, BCLX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tuh OCA], [http://pdbe.org/4tuh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tuh RCSB], [http://www.ebi.ac.uk/pdbsum/4tuh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tuh ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tuh OCA], [http://pdbe.org/4tuh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tuh RCSB], [http://www.ebi.ac.uk/pdbsum/4tuh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tuh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| Line 22: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
[[Category: Colman, P M]] | [[Category: Colman, P M]] | ||
[[Category: Czabotar, P E]] | [[Category: Czabotar, P E]] | ||
Revision as of 09:17, 22 November 2017
Bcl-xL in complex with inhibitor (Compound 10)
| |||||||||||
Categories: Human | Colman, P M | Czabotar, P E | Lessense, G | Smith, B J | Apoptosis | Drug design
