4b4z

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==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor==
==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor==
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<StructureSection load='4b4z' size='340' side='right' caption='[[4b4z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='4b4z' size='340' side='right'caption='[[4b4z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actsp Actsp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomadura_sp._r39 Actinomadura sp. r39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B4Z FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w79|1w79]], [[1w8q|1w8q]], [[1w8y|1w8y]], [[2vgj|2vgj]], [[2vgk|2vgk]], [[2wke|2wke]], [[2xdm|2xdm]], [[2xk1|2xk1]], [[2xln|2xln]], [[2y4a|2y4a]], [[2y55|2y55]], [[2y59|2y59]], [[3zvt|3zvt]], [[3zvw|3zvw]], [[4b4x|4b4x]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1w79|1w79]], [[1w8q|1w8q]], [[1w8y|1w8y]], [[2vgj|2vgj]], [[2vgk|2vgk]], [[2wke|2wke]], [[2xdm|2xdm]], [[2xk1|2xk1]], [[2xln|2xln]], [[2y4a|2y4a]], [[2y55|2y55]], [[2y59|2y59]], [[3zvt|3zvt]], [[3zvw|3zvw]], [[4b4x|4b4x]]</td></tr>
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
[[http://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
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==See Also==
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*[[Carboxypeptidase|Carboxypeptidase]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Actsp]]
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[[Category: Actinomadura sp. r39]]
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[[Category: Large Structures]]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
[[Category: Cannella, S E]]
[[Category: Cannella, S E]]

Revision as of 13:11, 13 March 2019

Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor

PDB ID 4b4z

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