3omj

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==Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding==
==Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding==
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<StructureSection load='3omj' size='340' side='right' caption='[[3omj]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
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<StructureSection load='3omj' size='340' side='right'caption='[[3omj]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3omj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OMJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OMJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3omj]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OMJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OMJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1P2:(23R,52R)-23,52-DIAMINO-5,11,17,28,34,40,46,57-OCTAMETHYL-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,64-ICOSAAZANONACYCLO[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]HEXAHEXACONTA-1(58),4(66),6,10(65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-HEXADECAENE-3,9,15,21,26,32,38,44,50,55-DECONE'>1P2</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1P2:(23R,52R)-23,52-DIAMINO-5,11,17,28,34,40,46,57-OCTAMETHYL-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,64-ICOSAAZANONACYCLO[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]HEXAHEXACONTA-1(58),4(66),6,10(65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-HEXADECAENE-3,9,15,21,26,32,38,44,50,55-DECONE'>1P2</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C38:5-IODO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>C38</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C38:5-IODO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>C38</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3omj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3omj OCA], [http://pdbe.org/3omj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3omj RCSB], [http://www.ebi.ac.uk/pdbsum/3omj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3omj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3omj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3omj OCA], [https://pdbe.org/3omj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3omj RCSB], [https://www.ebi.ac.uk/pdbsum/3omj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3omj ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Chenoweth, D M]]
[[Category: Chenoweth, D M]]
[[Category: Cyclic py-im polyamide]]
[[Category: Cyclic py-im polyamide]]
[[Category: Dna]]
[[Category: Dna]]

Revision as of 10:48, 18 May 2022

Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding

PDB ID 3omj

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