4nz9
From Proteopedia
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==Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor== | ==Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor== | ||
| - | <StructureSection load='4nz9' size='340' side='right' caption='[[4nz9]], [[Resolution|resolution]] 2.30Å' scene=''> | + | <StructureSection load='4nz9' size='340' side='right'caption='[[4nz9]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nz9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NZ9 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4nz9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staa3 Staa3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NZ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NZ9 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JT:1-(4-METHOXY-3-METHYLBENZYL)-5,6,7,8-TETRAHYDRO-1H-NAPHTHO[2,3-D]IMIDAZOLE'>1JT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1JT:1-(4-METHOXY-3-METHYLBENZYL)-5,6,7,8-TETRAHYDRO-1H-NAPHTHO[2,3-D]IMIDAZOLE'>1JT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabi, SAUSA300_0912 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367830 STAA3])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADPH,_Re-specific) Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.39 1.3.1.39] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADPH,_Re-specific) Enoyl-[acyl-carrier-protein] reductase (NADPH, Re-specific)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.39 1.3.1.39] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nz9 OCA], [http://pdbe.org/4nz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nz9 RCSB], [http://www.ebi.ac.uk/pdbsum/4nz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nz9 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nz9 OCA], [http://pdbe.org/4nz9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nz9 RCSB], [http://www.ebi.ac.uk/pdbsum/4nz9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nz9 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Enoyl-Acyl-Carrier Protein Reductase|Enoyl-Acyl-Carrier Protein Reductase]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Staa3]] | ||
[[Category: Johnson, M E]] | [[Category: Johnson, M E]] | ||
[[Category: Mehboob, S]] | [[Category: Mehboob, S]] | ||
Revision as of 08:43, 10 April 2019
Crystal Structure of FabI from S. aureus in complex with a novel benzimidazole inhibitor
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