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2w83

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==CRYSTAL STRUCTURE OF THE ARF6 GTPASE IN COMPLEX WITH A SPECIFIC EFFECTOR, JIP4==
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==Crystal structure of the ARF6 GTPase in complex with a specific effector, JIP4==
<StructureSection load='2w83' size='340' side='right' caption='[[2w83]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
<StructureSection load='2w83' size='340' side='right' caption='[[2w83]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w83 OCA], [http://pdbe.org/2w83 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w83 RCSB], [http://www.ebi.ac.uk/pdbsum/2w83 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w83 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w83 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w83 OCA], [http://pdbe.org/2w83 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w83 RCSB], [http://www.ebi.ac.uk/pdbsum/2w83 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w83 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[http://www.uniprot.org/uniprot/JIP4_HUMAN JIP4_HUMAN]] The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. Isoform 5 may play a role in spermatozoa-egg-interaction.<ref>PMID:14743216</ref> <ref>PMID:15693750</ref>
 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w8/2w83_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w8/2w83_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: Raynal, B]]
[[Category: Raynal, B]]
[[Category: Regazzoni, K]]
[[Category: Regazzoni, K]]
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[[Category: Alternative splicing]]
[[Category: Arf]]
[[Category: Arf]]
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[[Category: Coiled coil]]
[[Category: Coiled-coil]]
[[Category: Coiled-coil]]
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[[Category: Cytoplasm]]
[[Category: Effector]]
[[Category: Effector]]
[[Category: Er-golgi transport]]
[[Category: Er-golgi transport]]

Revision as of 08:55, 26 September 2018

Crystal structure of the ARF6 GTPase in complex with a specific effector, JIP4

2w83, resolution 1.93Å

Drag the structure with the mouse to rotate

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