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4pjv
From Proteopedia
(Difference between revisions)
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==Structure of PARP2 catalytic domain bound to inhibitor BMN 673== | ==Structure of PARP2 catalytic domain bound to inhibitor BMN 673== | ||
| - | <StructureSection load='4pjv' size='340' side='right' caption='[[4pjv]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='4pjv' size='340' side='right'caption='[[4pjv]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4pjv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PJV FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4pjv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PJV FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YQ:(8S,9R)-5-FLUORO-8-(4-FLUOROPHENYL)-9-(1-METHYL-1H-1,2,4-TRIAZOL-5-YL)-2,7,8,9-TETRAHYDRO-3H-PYRIDO[4,3,2-DE]PHTHALAZIN-3-ONE'>2YQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2YQ:(8S,9R)-5-FLUORO-8-(4-FLUOROPHENYL)-9-(1-METHYL-1H-1,2,4-TRIAZOL-5-YL)-2,7,8,9-TETRAHYDRO-3H-PYRIDO[4,3,2-DE]PHTHALAZIN-3-ONE'>2YQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pjt|4pjt]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4pjt|4pjt]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PARP2, ADPRT2, ADPRTL2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pjv OCA], [http://pdbe.org/4pjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pjv RCSB], [http://www.ebi.ac.uk/pdbsum/4pjv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pjv ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pjv OCA], [http://pdbe.org/4pjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4pjv RCSB], [http://www.ebi.ac.uk/pdbsum/4pjv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4pjv ProSAT]</span></td></tr> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Aoyagi-Scharber, M]] | [[Category: Aoyagi-Scharber, M]] | ||
[[Category: Edwards, T L]] | [[Category: Edwards, T L]] | ||
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[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
[[Category: Parp2]] | [[Category: Parp2]] | ||
| + | [[Category: Transferase-transferase inhibitor complex]] | ||
Revision as of 07:28, 17 April 2019
Structure of PARP2 catalytic domain bound to inhibitor BMN 673
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