4e4l
From Proteopedia
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==JAK1 kinase (JH1 domain) in complex with compound 30== | ==JAK1 kinase (JH1 domain) in complex with compound 30== | ||
| - | <StructureSection load='4e4l' size='340' side='right' caption='[[4e4l]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4e4l' size='340' side='right'caption='[[4e4l]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4e4l]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4e4l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E4L FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0NH:1-[4-METHYL-1-(METHYLSULFONYL)PIPERIDIN-4-YL]-1,6-DIHYDROIMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDINE'>0NH</scene> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0NH:1-[4-METHYL-1-(METHYLSULFONYL)PIPERIDIN-4-YL]-1,6-DIHYDROIMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDINE'>0NH</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e4l OCA], [https://pdbe.org/4e4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e4l RCSB], [https://www.ebi.ac.uk/pdbsum/4e4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e4l ProSAT]</span></td></tr> | |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN]] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Janus kinase|Janus kinase]] | + | *[[Janus kinase 3D structures|Janus kinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Eigenbrot | + | [[Category: Eigenbrot C]] |
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Revision as of 06:49, 28 September 2022
JAK1 kinase (JH1 domain) in complex with compound 30
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