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4iwh

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==Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei==
==Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei==
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<StructureSection load='4iwh' size='340' side='right' caption='[[4iwh]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='4iwh' size='340' side='right'caption='[[4iwh]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4iwh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Burta Burta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IWH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IWH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4iwh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_thailandensis_E264 Burkholderia thailandensis E264]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IWH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IWH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BTH_II0674, leuB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=271848 BURTA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iwh OCA], [https://pdbe.org/4iwh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iwh RCSB], [https://www.ebi.ac.uk/pdbsum/4iwh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iwh ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-isopropylmalate_dehydrogenase 3-isopropylmalate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.85 1.1.1.85] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iwh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iwh OCA], [http://pdbe.org/4iwh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4iwh RCSB], [http://www.ebi.ac.uk/pdbsum/4iwh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4iwh ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LEU3_BURTA LEU3_BURTA]] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
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[https://www.uniprot.org/uniprot/LEU3_BURTA LEU3_BURTA] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.[HAMAP-Rule:MF_01033]
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: 3-isopropylmalate dehydrogenase]]
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[[Category: Burkholderia thailandensis E264]]
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[[Category: Burta]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Aconitase]]
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[[Category: Gapdh]]
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[[Category: Glyceraldehyde-3-phosphate]]
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[[Category: Oxidoreductase]]
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[[Category: Ssgcid]]
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Revision as of 21:16, 16 November 2022

Crystal structure of a 3-isopropylmalate dehydrogenase from Burkholderia pseudomallei

PDB ID 4iwh

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