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3nb0

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Current revision (09:12, 6 September 2023) (edit) (undo)
 
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==Glucose-6-Phosphate activated form of Yeast Glycogen Synthase==
==Glucose-6-Phosphate activated form of Yeast Glycogen Synthase==
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<StructureSection load='3nb0' size='340' side='right' caption='[[3nb0]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
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<StructureSection load='3nb0' size='340' side='right'caption='[[3nb0]], [[Resolution|resolution]] 2.41&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3nb0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NB0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NB0 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3nb0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NB0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NB0 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.406&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1rzu|1rzu]], [[2bis|2bis]], [[2qzs|2qzs]], [[3naz|3naz]], [[3nch|3nch]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G6P:ALPHA-D-GLUCOSE-6-PHOSPHATE'>G6P</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GSY2, L8479.8, YLR258W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nb0 OCA], [https://pdbe.org/3nb0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nb0 RCSB], [https://www.ebi.ac.uk/pdbsum/3nb0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nb0 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycogen(starch)_synthase Glycogen(starch) synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.11 2.4.1.11] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nb0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nb0 OCA], [http://pdbe.org/3nb0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nb0 RCSB], [http://www.ebi.ac.uk/pdbsum/3nb0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nb0 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GYS2_YEAST GYS2_YEAST]] Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Is believed to regulate the synthesis of glycogen.
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[https://www.uniprot.org/uniprot/GYS2_YEAST GYS2_YEAST] Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan. Is believed to regulate the synthesis of glycogen.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nb/3nb0_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nb/3nb0_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 18824]]
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[[Category: Large Structures]]
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[[Category: Baskaran, S]]
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[[Category: Saccharomyces cerevisiae]]
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[[Category: Hurley, T D]]
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[[Category: Baskaran S]]
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[[Category: Allosteric activation]]
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[[Category: Hurley TD]]
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[[Category: Glucose-6-phosphate]]
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[[Category: Glycogen synthase]]
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[[Category: Transferase]]
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[[Category: Yeast]]
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Current revision

Glucose-6-Phosphate activated form of Yeast Glycogen Synthase

PDB ID 3nb0

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