1mzp

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[[Image:1mzp.gif|left|200px]]
[[Image:1mzp.gif|left|200px]]
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{{Structure
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|PDB= 1mzp |SIZE=350|CAPTION= <scene name='initialview01'>1mzp</scene>, resolution 2.65&Aring;
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The line below this paragraph, containing "STRUCTURE_1mzp", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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{{STRUCTURE_1mzp| PDB=1mzp | SCENE= }}
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|RELATEDENTRY=[[1ad2|1AD2]], [[1csj|1CSJ]], [[1dwu|1DWU]], [[1jj2|1JJ2]], [[1giy|1GIY]], [[1lnr|1LNR]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mzp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mzp OCA], [http://www.ebi.ac.uk/pdbsum/1mzp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1mzp RCSB]</span>
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'''Structure of the L1 protuberance in the ribosome'''
'''Structure of the L1 protuberance in the ribosome'''
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[[Category: Tishchenko, S.]]
[[Category: Tishchenko, S.]]
[[Category: Zimmermann, R.]]
[[Category: Zimmermann, R.]]
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[[Category: ribosomal protein]]
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[[Category: Ribosomal protein]]
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[[Category: ribosome]]
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[[Category: Ribosome]]
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[[Category: rna-protein complex]]
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[[Category: Rna-protein complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 01:54:32 2008''
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Revision as of 22:54, 2 May 2008

Image:1mzp.gif

Template:STRUCTURE 1mzp

Structure of the L1 protuberance in the ribosome


Overview

The L1 protuberance of the 50S ribosomal subunit is implicated in the release/disposal of deacylated tRNA from the E site. The apparent mobility of this ribosomal region has thus far prevented an accurate determination of its three-dimensional structure within either the 50S subunit or the 70S ribosome. Here we report the crystal structure at 2.65 A resolution of ribosomal protein L1 from Sulfolobus acidocaldarius in complex with a specific 55-nucleotide fragment of 23S rRNA from Thermus thermophilus. This structure fills a major gap in current models of the 50S ribosomal subunit. The conformations of L1 and of the rRNA fragment differ dramatically from those within the crystallographic model of the T. thermophilus 70S ribosome. Incorporation of the L1-rRNA complex into the structural models of the T. thermophilus 70S ribosome and the Deinococcus radiodurans 50S subunit gives a reliable representation of most of the L1 protuberance within the ribosome.

About this Structure

1MZP is a Single protein structure of sequence from Sulfolobus acidocaldarius. Full crystallographic information is available from OCA.

Reference

Structure of the L1 protuberance in the ribosome., Nikulin A, Eliseikina I, Tishchenko S, Nevskaya N, Davydova N, Platonova O, Piendl W, Selmer M, Liljas A, Drygin D, Zimmermann R, Garber M, Nikonov S, Nat Struct Biol. 2003 Feb;10(2):104-8. PMID:12514741 Page seeded by OCA on Sat May 3 01:54:32 2008

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