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4nf2
From Proteopedia
(Difference between revisions)
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==Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline== | ==Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline== | ||
| - | <StructureSection load='4nf2' size='340' side='right' caption='[[4nf2]], [[Resolution|resolution]] 1.74Å' scene=''> | + | <StructureSection load='4nf2' size='340' side='right'caption='[[4nf2]], [[Resolution|resolution]] 1.74Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4nf2]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4nf2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_ames_"ancestor" Bacillus anthracis ames "ancestor"]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NF2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NF2 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CP:PHOSPHORIC+ACID+MONO(FORMAMIDE)ESTER'>CP</scene>, <scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CP:PHOSPHORIC+ACID+MONO(FORMAMIDE)ESTER'>CP</scene>, <scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr> |
| - | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ep1|4ep1]]</td></tr> | + | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4ep1|4ep1]]</div></td></tr> |
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argF, BAS4036, BA_4351, GBAA_4351 ([ | + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">argF, BAS4036, BA_4351, GBAA_4351 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=261594 Bacillus anthracis Ames "Ancestor"])</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ornithine_carbamoyltransferase Ornithine carbamoyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.3 2.1.3.3] </span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nf2 OCA], [https://pdbe.org/4nf2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nf2 RCSB], [https://www.ebi.ac.uk/pdbsum/4nf2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nf2 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/OTC_BACAN OTC_BACAN]] Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline, which is a substrate for argininosuccinate synthetase, the enzyme involved in the final step in arginine biosynthesis (By similarity).[HAMAP-Rule:MF_01109] |
==See Also== | ==See Also== | ||
| - | *[[Ornithine carbamoyltransferase|Ornithine carbamoyltransferase]] | + | *[[Ornithine carbamoyltransferase 3D structures|Ornithine carbamoyltransferase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Bacillus anthracis ames ancestor]] | [[Category: Bacillus anthracis ames ancestor]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Ornithine carbamoyltransferase]] | [[Category: Ornithine carbamoyltransferase]] | ||
[[Category: Anderson, W F]] | [[Category: Anderson, W F]] | ||
Revision as of 10:04, 13 April 2022
Crystal structure of anabolic ornithine carbamoyltransferase from Bacillus anthracis in complex with carbamoyl phosphate and L-norvaline
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Categories: Bacillus anthracis ames ancestor | Large Structures | Ornithine carbamoyltransferase | Anderson, W F | Structural genomic | Cymborowski, M T | Handing, K | Minor, W | Shabalin, I G | Shuvalova, L | Stam, J | Winsor, J | Carbamoyl phosphate | Csgid | L-ornithine | National institute of allergy and infectious disease | Niaid | Transferase
