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3uwp

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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.
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==See Also==
 
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*[[Histone methyltransferase|Histone methyltransferase]]
 
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</StructureSection>
</StructureSection>

Revision as of 10:09, 8 November 2017

Crystal structure of Dot1l in complex with 5-iodotubercidin

3uwp, resolution 2.05Å

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