3qk3

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==Crystal structure of human beta-crystallin B3==
==Crystal structure of human beta-crystallin B3==
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<StructureSection load='3qk3' size='340' side='right' caption='[[3qk3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3qk3' size='340' side='right'caption='[[3qk3]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3qk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QK3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3qk3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QK3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRYBB3, CRYB3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CRYBB3, CRYB3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qk3 OCA], [http://pdbe.org/3qk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3qk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qk3 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qk3 OCA], [https://pdbe.org/3qk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qk3 RCSB], [https://www.ebi.ac.uk/pdbsum/3qk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qk3 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN]] Non-syndromic congenital cataract. Cataract, congenital, nuclear, autosomal recessive 2 (CATCN2) [MIM:[http://omim.org/entry/609741 609741]]: A congenital cataract affecting the central nucleus of the eye. Nucler cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:15914629</ref>
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[[https://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN]] Non-syndromic congenital cataract. Cataract, congenital, nuclear, autosomal recessive 2 (CATCN2) [MIM:[https://omim.org/entry/609741 609741]]: A congenital cataract affecting the central nucleus of the eye. Nucler cataracts are often not highly visually significant. The density of the opacities varies greatly from fine dots to a dense, white and chalk-like, central cataract. The condition is usually bilateral. Nuclear cataracts are often combined with opacified cortical fibers encircling the nuclear opacity, which are referred to as cortical riders. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:15914629</ref>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN]] Crystallins are the dominant structural components of the vertebrate eye lens.
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[[https://www.uniprot.org/uniprot/CRBB3_HUMAN CRBB3_HUMAN]] Crystallins are the dominant structural components of the vertebrate eye lens.
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==See Also==
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*[[Crystallin 3D structures|Crystallin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Human]]
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[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]

Revision as of 06:12, 8 June 2022

Crystal structure of human beta-crystallin B3

PDB ID 3qk3

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