4l9o
From Proteopedia
(Difference between revisions)
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<StructureSection load='4l9o' size='340' side='right' caption='[[4l9o]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4l9o' size='340' side='right' caption='[[4l9o]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4l9o]] is a 2 chain structure | + | <table><tr><td colspan='2'>[[4l9o]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L9O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4L9O FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
| - | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SEC13, PP7435_Chr4-0919 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=644223 Komagataella pastoris (strain GS115 / ATCC 20864)])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l9o OCA], [http://pdbe.org/4l9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l9o RCSB], [http://www.ebi.ac.uk/pdbsum/4l9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l9o ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l9o OCA], [http://pdbe.org/4l9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l9o RCSB], [http://www.ebi.ac.uk/pdbsum/4l9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l9o ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | == Function == | ||
| - | [[http://www.uniprot.org/uniprot/SEC13_PICPG SEC13_PICPG]] Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
Revision as of 09:19, 3 August 2017
Crystal Structure of the Sec13-Sec16 blade-inserted complex from Pichia pastoris
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