4esv

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{{Large structure}}
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==A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates==
==A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates==
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<StructureSection load='4esv' size='340' side='right' caption='[[4esv]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='4esv' size='340' side='right'caption='[[4esv]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4esv]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. The December 2013 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA Helicase'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2013_12 10.2210/rcsb_pdb/mom_2013_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ESV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4esv]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. The December 2013 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''DNA Helicase'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2013_12 10.2210/rcsb_pdb/mom_2013_12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ESV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ESV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dnaB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1422 ATCC 12980])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4esv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esv OCA], [https://pdbe.org/4esv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4esv RCSB], [https://www.ebi.ac.uk/pdbsum/4esv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4esv ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4esv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4esv OCA], [http://pdbe.org/4esv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4esv RCSB], [http://www.ebi.ac.uk/pdbsum/4esv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4esv ProSAT]</span></td></tr>
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</table>
</table>
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{{Large structure}}
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== Function ==
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[https://www.uniprot.org/uniprot/Q9X4C9_GEOSE Q9X4C9_GEOSE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 12980]]
 
[[Category: DNA Helicase]]
[[Category: DNA Helicase]]
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[[Category: DNA helicase]]
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[[Category: Geobacillus stearothermophilus]]
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[[Category: Large Structures]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Eliason, W K]]
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[[Category: Synthetic construct]]
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[[Category: Itsathitphaisarn, O]]
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[[Category: Eliason WK]]
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[[Category: Steitz, T A]]
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[[Category: Itsathitphaisarn O]]
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[[Category: Wang, J]]
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[[Category: Steitz TA]]
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[[Category: Wing, R A]]
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[[Category: Wang J]]
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[[Category: Helicase]]
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[[Category: Wing RA]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Reca fold]]
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Revision as of 04:13, 7 October 2022

A New Twist on the Translocation Mechanism of Helicases from the Structure of DnaB with its Substrates

PDB ID 4esv

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