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1n56

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[[Image:1n56.gif|left|200px]]
[[Image:1n56.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1n56 |SIZE=350|CAPTION= <scene name='initialview01'>1n56</scene>, resolution 2.4&Aring;
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The line below this paragraph, containing "STRUCTURE_1n56", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=3DR:1&#39;,2&#39;-DIDEOXYRIBOFURANOSE-5&#39;-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=ATP:ADENOSINE-5&#39;-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= dpo4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])
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-->
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|DOMAIN=
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{{STRUCTURE_1n56| PDB=1n56 | SCENE= }}
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|RELATEDENTRY=[[1jx4|1JX4]], [[1jxl|1JXL]], [[1n48|1N48]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1n56 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n56 OCA], [http://www.ebi.ac.uk/pdbsum/1n56 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1n56 RCSB]</span>
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}}
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'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''
'''Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion'''
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[[Category: Woodgate, R.]]
[[Category: Woodgate, R.]]
[[Category: Yang, W.]]
[[Category: Yang, W.]]
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[[Category: dna lesion bypass]]
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[[Category: Dna lesion bypass]]
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[[Category: dna polymerase]]
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[[Category: Dna polymerase]]
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[[Category: protein-dna complex]]
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[[Category: Protein-dna complex]]
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[[Category: y-family]]
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[[Category: Y-family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:06:34 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:25:33 2008''
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Revision as of 23:06, 2 May 2008

Image:1n56.gif

Template:STRUCTURE 1n56

Y-family DNA polymerase Dpo4 in complex with DNA containing abasic lesion


Overview

Studies on several recently discovered error-prone DNA polymerases reveal novel structures that may explain the low fidelity of this general class of enzymes, a number of which are involved in the replicative bypass (translesion synthesis) of base damage in DNA.

About this Structure

1N56 is a Single protein structure of sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

Error-prone DNA polymerases: novel structures and the benefits of infidelity., Friedberg EC, Fischhaber PL, Kisker C, Cell. 2001 Oct 5;107(1):9-12. PMID:11595180 Page seeded by OCA on Sat May 3 02:06:34 2008

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OCA

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