1n5b
From Proteopedia
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'''Crystal Structure Of The Yersinia enterocolitica Molecular Chaperone Syce''' | '''Crystal Structure Of The Yersinia enterocolitica Molecular Chaperone Syce''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | 1N5B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. This structure supersedes the now removed PDB entry | + | 1N5B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Yersinia_enterocolitica Yersinia enterocolitica]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1md1 1md1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N5B OCA]. |
==Reference== | ==Reference== | ||
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[[Category: McKay, D B.]] | [[Category: McKay, D B.]] | ||
[[Category: Trame, C B.]] | [[Category: Trame, C B.]] | ||
| - | [[Category: | + | [[Category: Molecular chaperone]] |
| - | [[Category: | + | [[Category: Type iii secretion system]] |
| - | [[Category: | + | [[Category: Yersinia enterocolitica]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:06:49 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 23:06, 2 May 2008
Crystal Structure Of The Yersinia enterocolitica Molecular Chaperone Syce
Overview
The crystal structure of the Yersinia enterocolitica molecular-chaperone protein SycE, which specifically binds the YopE protein, has been solved to 2.0 A resolution by molecular replacement. The crystal contains two SycE dimers per asymmetric unit; a novel feature of this crystal, when compared with closely related SycE structures, is a well ordered carboxy-terminal peptide in one protomer of each dimer. The peptide binds a hydrophobic patch of a neighboring molecule in a manner similar to that seen in a SycE-YopE chaperone-target complex, suggestive of low-affinity 'self-binding' through which the carboxy-terminal peptide might suppress counterproductive interactions with non-target proteins in vivo.
About this Structure
1N5B is a Single protein structure of sequence from Yersinia enterocolitica. This structure supersedes the now removed PDB entry 1md1. Full crystallographic information is available from OCA.
Reference
Structure of the Yersinia enterocolitica molecular-chaperone protein SycE., Trame CB, McKay DB, Acta Crystallogr D Biol Crystallogr. 2003 Feb;59(Pt 2):389-92. Epub 2003, Jan 23. PMID:12554962 Page seeded by OCA on Sat May 3 02:06:49 2008
