This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4kbm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
==Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex==
==Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex==
-
<StructureSection load='4kbm' size='340' side='right' caption='[[4kbm]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
+
<StructureSection load='4kbm' size='340' side='right'caption='[[4kbm]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4kbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBM FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4kbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KBM FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kbj|4kbj]]</td></tr>
+
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbm OCA], [https://pdbe.org/4kbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kbm RCSB], [https://www.ebi.ac.uk/pdbsum/4kbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbm ProSAT]</span></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MT0695, MTCI376.08c, rpoB, Rv0667 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884]), carD, MT3689, Rv3583c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbm OCA], [http://pdbe.org/4kbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kbm RCSB], [http://www.ebi.ac.uk/pdbsum/4kbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbm ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/RPOB_MYCTU RPOB_MYCTU]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321] [[http://www.uniprot.org/uniprot/CARD_MYCTU CARD_MYCTU]] Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for replication and persistence during infection of mice.<ref>PMID:19596241</ref> <ref>PMID:22904282</ref>
+
[https://www.uniprot.org/uniprot/RPOB_MYCTU RPOB_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 21:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: DNA-directed RNA polymerase]]
+
[[Category: Large Structures]]
-
[[Category: Gulten, G]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Sacchettini, J C]]
+
[[Category: Gulten G]]
-
[[Category: Structural genomic]]
+
[[Category: Sacchettini JC]]
-
[[Category: Card]]
+
-
[[Category: Dna]]
+
-
[[Category: Dna-dependent rna polymerase]]
+
-
[[Category: Protein-protein complex]]
+
-
[[Category: Sigma factor]]
+
-
[[Category: Tbsgc]]
+
-
[[Category: Transcription regulator]]
+
-
[[Category: Transferase-transcription complex]]
+
-
[[Category: Tudor]]
+

Revision as of 11:51, 30 November 2022

Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex

PDB ID 4kbm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4kbm"
Personal tools