5ef8
From Proteopedia
(Difference between revisions)
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==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with panobinostat== | ==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with panobinostat== | ||
| - | <StructureSection load='5ef8' size='340' side='right' caption='[[5ef8]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='5ef8' size='340' side='right'caption='[[5ef8]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5ef8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EF8 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5ef8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EF8 FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LBH:PANOBINOSTAT'>LBH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=LBH:PANOBINOSTAT'>LBH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5edu|5edu]], [[5eef|5eef]], [[5eei|5eei]], [[5eek|5eek]], [[5eem|5eem]], [[5een|5een]], [[5ef7|5ef7]], [[5efb|5efb]], [[5efg|5efg]], [[5efh|5efh]], [[5efj|5efj]], [[5efk|5efk]], [[5efn|5efn]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5edu|5edu]], [[5eef|5eef]], [[5eei|5eei]], [[5eek|5eek]], [[5eem|5eem]], [[5een|5een]], [[5ef7|5ef7]], [[5efb|5efb]], [[5efg|5efg]], [[5efh|5efh]], [[5efj|5efj]], [[5efk|5efk]], [[5efn|5efn]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hdac6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ef8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ef8 OCA], [http://pdbe.org/5ef8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ef8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ef8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ef8 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ef8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ef8 OCA], [http://pdbe.org/5ef8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ef8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ef8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ef8 ProSAT]</span></td></tr> | ||
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</div> | </div> | ||
<div class="pdbe-citations 5ef8" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5ef8" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Brachidanio rerio]] | ||
[[Category: Histone deacetylase]] | [[Category: Histone deacetylase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Christianson, D W]] | [[Category: Christianson, D W]] | ||
[[Category: Hai, Y]] | [[Category: Hai, Y]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 11:32, 25 December 2019
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with panobinostat
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