This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5eei
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA== | ==Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA== | ||
| - | <StructureSection load='5eei' size='340' side='right' caption='[[5eei]], [[Resolution|resolution]] 1.32Å' scene=''> | + | <StructureSection load='5eei' size='340' side='right'caption='[[5eei]], [[Resolution|resolution]] 1.32Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5eei]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EEI FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5eei]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EEI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EEI FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SHH:OCTANEDIOIC+ACID+HYDROXYAMIDE+PHENYLAMIDE'>SHH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SHH:OCTANEDIOIC+ACID+HYDROXYAMIDE+PHENYLAMIDE'>SHH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5edu|5edu]], [[5eef|5eef]], [[5eek|5eek]], [[5eem|5eem]], [[5een|5een]], [[5ef7|5ef7]], [[5ef8|5ef8]], [[5efb|5efb]], [[5efg|5efg]], [[5efh|5efh]], [[5efj|5efj]], [[5efk|5efk]], [[5efn|5efn]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5edu|5edu]], [[5eef|5eef]], [[5eek|5eek]], [[5eem|5eem]], [[5een|5een]], [[5ef7|5ef7]], [[5ef8|5ef8]], [[5efb|5efb]], [[5efg|5efg]], [[5efh|5efh]], [[5efj|5efj]], [[5efk|5efk]], [[5efn|5efn]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hdac6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histone_deacetylase Histone deacetylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.98 3.5.1.98] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eei OCA], [http://pdbe.org/5eei PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eei RCSB], [http://www.ebi.ac.uk/pdbsum/5eei PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eei ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eei OCA], [http://pdbe.org/5eei PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eei RCSB], [http://www.ebi.ac.uk/pdbsum/5eei PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eei ProSAT]</span></td></tr> | ||
| Line 18: | Line 19: | ||
</div> | </div> | ||
<div class="pdbe-citations 5eei" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 5eei" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Histone deacetylase 3D structures|Histone deacetylase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Brachidanio rerio]] | ||
[[Category: Histone deacetylase]] | [[Category: Histone deacetylase]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Christianson, D W]] | [[Category: Christianson, D W]] | ||
[[Category: Hai, Y]] | [[Category: Hai, Y]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 11:32, 25 December 2019
Crystal structure of Danio rerio histone deacetylase 6 catalytic domain 2 in complex with SAHA
| |||||||||||
