Poly (ADP-ribose) glycohydrolase
From Proteopedia
(Difference between revisions)
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**[[3sig]] – TcPARG + ADP-ribose <br /> | **[[3sig]] – TcPARG + ADP-ribose <br /> | ||
**[[4epp]] – TtPARG + ADP-ribose - ''Tetrahymena thermophila'' <br /> | **[[4epp]] – TtPARG + ADP-ribose - ''Tetrahymena thermophila'' <br /> | ||
| - | **[[4l2h]] – TtPARG (mutant) + ADP-ribose <br /> | + | **[[4l2h]], [[5a7r]] – TtPARG (mutant) + ADP-ribose <br /> |
**[[4b1h]] – hPARG catalytic domain (mutant) + ADP-ribose<br /> | **[[4b1h]] – hPARG catalytic domain (mutant) + ADP-ribose<br /> | ||
**[[4na0]] – mPARG catalytic domain + ADP-ribose<br /> | **[[4na0]] – mPARG catalytic domain + ADP-ribose<br /> | ||
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**[[3uel]] – rPARG catalytic domain + inhibitor <br /> | **[[3uel]] – rPARG catalytic domain + inhibitor <br /> | ||
**[[4epq]] – TtPARG + inhibitor <br /> | **[[4epq]] – TtPARG + inhibitor <br /> | ||
| - | **[[4b1i]], [[4b1j]] – hPARG catalytic domain (mutant) + inhibitor<br /> | + | **[[4b1i]], [[4b1j]], [[5lhb]] – hPARG catalytic domain (mutant) + inhibitor<br /> |
**[[4na4]] – mPARG catalytic domain + inhibitor <br /> | **[[4na4]] – mPARG catalytic domain + inhibitor <br /> | ||
}} | }} | ||
Revision as of 08:18, 12 September 2017
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3D Structures of poly (ADP-ribose) glycohydrolase
Updated on 12-September-2017
References
- ↑ Herceg Z, Wang ZQ. Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat Res. 2001 Jun 2;477(1-2):97-110. PMID:11376691
- ↑ Virag L, Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev. 2002 Sep;54(3):375-429. PMID:12223530
- ↑ Slade D, Dunstan MS, Barkauskaite E, Weston R, Lafite P, Dixon N, Ahel M, Leys D, Ahel I. The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase. Nature. 2011 Sep 4. doi: 10.1038/nature10404. PMID:21892188 doi:10.1038/nature10404
