1nak

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[[Image:1nak.gif|left|200px]]
[[Image:1nak.gif|left|200px]]
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{{Structure
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|PDB= 1nak |SIZE=350|CAPTION= <scene name='initialview01'>1nak</scene>, resolution 2.57&Aring;
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The line below this paragraph, containing "STRUCTURE_1nak", creates the "Structure Box" on the page.
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|SITE=
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{{STRUCTURE_1nak| PDB=1nak | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nak OCA], [http://www.ebi.ac.uk/pdbsum/1nak PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nak RCSB]</span>
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'''IGG1 FAB FRAGMENT (83.1) COMPLEX WITH 16-RESIDUE PEPTIDE (RESIDUES 304-321 OF HIV-1 GP120 (MN ISOLATE))'''
'''IGG1 FAB FRAGMENT (83.1) COMPLEX WITH 16-RESIDUE PEPTIDE (RESIDUES 304-321 OF HIV-1 GP120 (MN ISOLATE))'''
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==About this Structure==
==About this Structure==
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1NAK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAK OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NAK OCA].
==Reference==
==Reference==
Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop., Stanfield RL, Ghiara JB, Ollmann Saphire E, Profy AT, Wilson IA, Virology. 2003 Oct 10;315(1):159-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14592768 14592768]
Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop., Stanfield RL, Ghiara JB, Ollmann Saphire E, Profy AT, Wilson IA, Virology. 2003 Oct 10;315(1):159-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14592768 14592768]
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[[Category: Mus musculus]]
 
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[[Category: Protein complex]]
 
[[Category: Ghiara, J B.]]
[[Category: Ghiara, J B.]]
[[Category: Profy, A T.]]
[[Category: Profy, A T.]]
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[[Category: Stanfield, R L.]]
[[Category: Stanfield, R L.]]
[[Category: Wilson, I A.]]
[[Category: Wilson, I A.]]
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[[Category: immunoglobulin fold]]
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[[Category: Immunoglobulin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:17:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:27:39 2008''
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Revision as of 23:17, 2 May 2008

Image:1nak.gif

Template:STRUCTURE 1nak

IGG1 FAB FRAGMENT (83.1) COMPLEX WITH 16-RESIDUE PEPTIDE (RESIDUES 304-321 OF HIV-1 GP120 (MN ISOLATE))


Overview

The crystal structure of the human immunodeficiency virus type 1 (HIV-1) neutralizing, murine Fab 83.1 in complex with an HIV-1 gp120 V3 peptide has been determined to 2.57 A resolution. The conformation of the V3 loop peptide in complex with Fab 83.1 is very similar to V3 conformations seen previously with two other neutralizing Fabs, 50.1 and 59.1. The repeated identification of this same V3 conformation in complex with three very different, neutralizing antibodies indicates that it is a highly preferred structure for V3 loops on some strains of the HIV-1 virus.

About this Structure

Full crystallographic information is available from OCA.

Reference

Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop., Stanfield RL, Ghiara JB, Ollmann Saphire E, Profy AT, Wilson IA, Virology. 2003 Oct 10;315(1):159-73. PMID:14592768 Page seeded by OCA on Sat May 3 02:17:52 2008

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