1nbw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1nbw.jpg|left|200px]]
[[Image:1nbw.jpg|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1nbw |SIZE=350|CAPTION= <scene name='initialview01'>1nbw</scene>, resolution 2.4&Aring;
+
The line below this paragraph, containing "STRUCTURE_1nbw", creates the "Structure Box" on the page.
-
|SITE=
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= dhaB4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae]), orf2b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 Klebsiella pneumoniae])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1nbw| PDB=1nbw | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nbw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nbw OCA], [http://www.ebi.ac.uk/pdbsum/1nbw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nbw RCSB]</span>
+
-
}}
+
'''Glycerol dehydratase reactivase'''
'''Glycerol dehydratase reactivase'''
Line 29: Line 26:
[[Category: Liao, D I.]]
[[Category: Liao, D I.]]
[[Category: Reiss, L.]]
[[Category: Reiss, L.]]
-
[[Category: actin-like atpase domain]]
+
[[Category: Actin-like atpase domain]]
-
[[Category: beta/beta/alpha swiveling domain]]
+
[[Category: Beta/beta/alpha swiveling domain]]
-
[[Category: glycerol dehydratase]]
+
[[Category: Glycerol dehydratase]]
-
[[Category: molecular chaperone]]
+
[[Category: Molecular chaperone]]
-
[[Category: reactivase]]
+
[[Category: Reactivase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:20:45 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:28:13 2008''
+

Revision as of 23:20, 2 May 2008

Image:1nbw.jpg

Template:STRUCTURE 1nbw

Glycerol dehydratase reactivase


Overview

The function of glycerol dehydratase (GDH) reactivase is to remove damaged coenzyme B(12) from GDH that has suffered mechanism-based inactivation. The structure of GDH reactivase from Klebsiella pneumoniae was determined at 2.4 A resolution by the single isomorphous replacement with anomalous signal (SIR/AS) method. Each tetramer contains two elongated 63 kDa alpha subunits and two globular 14 kDa beta subunits. The alpha subunit contains structural features resembling both GroEL and Hsp70 groups of chaperones, and it appears chaperone like in its interactions with ATP. The fold of the beta subunit resembles that of the beta subunit of glycerol dehydratase, except that it lacks some coenzyme B(12) binding elements. A hypothesis for the reactivation mechanism of reactivase is proposed based on these structural features.

About this Structure

1NBW is a Protein complex structure of sequences from Klebsiella pneumoniae. Full crystallographic information is available from OCA.

Reference

Structure of glycerol dehydratase reactivase: a new type of molecular chaperone., Liao DI, Reiss L, Turner I, Dotson G, Structure. 2003 Jan;11(1):109-19. PMID:12517345 Page seeded by OCA on Sat May 3 02:20:45 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nbw"
Personal tools