1nci

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[[Image:1nci.gif|left|200px]]
[[Image:1nci.gif|left|200px]]
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{{Structure
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|PDB= 1nci |SIZE=350|CAPTION= <scene name='initialview01'>1nci</scene>, resolution 2.1&Aring;
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The line below this paragraph, containing "STRUCTURE_1nci", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=IUM:URANYL+(VI)+ION'>IUM</scene>
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{{STRUCTURE_1nci| PDB=1nci | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nci FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nci OCA], [http://www.ebi.ac.uk/pdbsum/1nci PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nci RCSB]</span>
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'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''
'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''
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[[Category: Shapiro, L.]]
[[Category: Shapiro, L.]]
[[Category: Thompson, A.]]
[[Category: Thompson, A.]]
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[[Category: cadherin]]
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[[Category: Cadherin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:22:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:28:31 2008''
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Revision as of 23:22, 2 May 2008

Image:1nci.gif

Template:STRUCTURE 1nci

STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS


Overview

Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.

About this Structure

1NCI is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471 Page seeded by OCA on Sat May 3 02:22:09 2008

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