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1nch

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[[Image:1nch.gif|left|200px]]
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{{Structure
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nch FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nch OCA], [http://www.ebi.ac.uk/pdbsum/1nch PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nch RCSB]</span>
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'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''
'''STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS'''
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[[Category: Shapiro, L.]]
[[Category: Shapiro, L.]]
[[Category: Thompson, A.]]
[[Category: Thompson, A.]]
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[[Category: cadherin]]
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[[Category: Cadherin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:22:08 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:28:28 2008''
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Revision as of 23:22, 2 May 2008

Image:1nch.gif

Template:STRUCTURE 1nch

STRUCTURAL BASIS OF CELL-CELL ADHESION BY CADHERINS


Overview

Crystal structures of the amino-terminal domain of N-cadherin provide a picture at the atomic level of a specific adhesive contact between cells. A repeated set of dimer interfaces is common to the structure in three lattices. These interactions combine to form a linear zipper of molecules that mirrors the linear structure of the intracellular filaments with which cadherins associate. This cell-adhesion zipper may provide a mechanism to marshal individual molecular adhesive interactions into strong bonds between cells.

About this Structure

1NCH is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Structural basis of cell-cell adhesion by cadherins., Shapiro L, Fannon AM, Kwong PD, Thompson A, Lehmann MS, Grubel G, Legrand JF, Als-Nielsen J, Colman DR, Hendrickson WA, Nature. 1995 Mar 23;374(6520):327-37. PMID:7885471 Page seeded by OCA on Sat May 3 02:22:08 2008

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