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4q5v
From Proteopedia
(Difference between revisions)
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==Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin== | ==Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin== | ||
| - | <StructureSection load='4q5v' size='340' side='right' caption='[[4q5v]], [[Resolution|resolution]] 2.52Å' scene=''> | + | <StructureSection load='4q5v' size='340' side='right'caption='[[4q5v]], [[Resolution|resolution]] 2.52Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4q5v]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q5V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q5V FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4q5v]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q5V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q5V FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2ZE:(3R,4R,4AR,6AS,8R,9R,11AS,11BS)-4,9-BIS(HYDROXYMETHYL)-4,11B-DIMETHYLTETRADECAHYDRO-8,11A-METHANOCYCLOHEPTA[A]NAPHTHALENE-3,9-DIOL'>2ZE</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2ZE:(3R,4R,4AR,6AS,8R,9R,11AS,11BS)-4,9-BIS(HYDROXYMETHYL)-4,11B-DIMETHYLTETRADECAHYDRO-8,11A-METHANOCYCLOHEPTA[A]NAPHTHALENE-3,9-DIOL'>2ZE</scene></td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">POLA1, POLA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q5v OCA], [http://pdbe.org/4q5v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q5v RCSB], [http://www.ebi.ac.uk/pdbsum/4q5v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q5v ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q5v OCA], [http://pdbe.org/4q5v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q5v RCSB], [http://www.ebi.ac.uk/pdbsum/4q5v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q5v ProSAT]</span></td></tr> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: DNA-directed DNA polymerase]] | [[Category: DNA-directed DNA polymerase]] | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Babayeva, N D]] | [[Category: Babayeva, N D]] | ||
[[Category: Baranovskiy, A G]] | [[Category: Baranovskiy, A G]] | ||
Revision as of 09:10, 24 April 2019
Crystal structure of the catalytic core of human DNA polymerase alpha in ternary complex with an RNA-primed DNA template and aphidicolin
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