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1nik

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[[Image:1nik.gif|left|200px]]
[[Image:1nik.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 1nik |SIZE=350|CAPTION= <scene name='initialview01'>1nik</scene>, resolution 4.10&Aring;
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The line below this paragraph, containing "STRUCTURE_1nik", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=UNK:UNKNOWN'>UNK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_1nik| PDB=1nik | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nik OCA], [http://www.ebi.ac.uk/pdbsum/1nik PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nik RCSB]</span>
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}}
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'''Wild Type RNA Polymerase II'''
'''Wild Type RNA Polymerase II'''
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[[Category: Bushnell, D A.]]
[[Category: Bushnell, D A.]]
[[Category: Kornberg, R D.]]
[[Category: Kornberg, R D.]]
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[[Category: transferase]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:34:39 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:30:51 2008''
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Revision as of 23:34, 2 May 2008

Image:1nik.gif

Template:STRUCTURE 1nik

Wild Type RNA Polymerase II


Overview

The x-ray structure of complete RNA polymerase II from Saccharomyces cerevisiae has been determined, including a heterodimer of subunits Rpb4 and Rpb7 not present in previous "core" polymerase II structures. The heterodimer maintains the polymerase in the conformation of a transcribing complex, may bind RNA as it emerges from the enzyme, and is in a position to interact with general transcription factors and the Mediator of transcriptional regulation.

About this Structure

1NIK is a Protein complex structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Complete, 12-subunit RNA polymerase II at 4.1-A resolution: implications for the initiation of transcription., Bushnell DA, Kornberg RD, Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):6969-73. Epub 2003 May 13. PMID:12746498 Page seeded by OCA on Sat May 3 02:34:39 2008

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OCA

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