4fgz

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==Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine==
==Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine==
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<StructureSection load='4fgz' size='340' side='right' caption='[[4fgz]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
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<StructureSection load='4fgz' size='340' side='right'caption='[[4fgz]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4fgz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafa Plafa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FGZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FGZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4fgz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FGZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CQA:4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL'>CQA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CQA:4-[(7-CHLOROQUINOLIN-4-YL)AMINO]-2-[(DIETHYLAMINO)METHYL]PHENOL'>CQA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 PLAFA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fgz OCA], [https://pdbe.org/4fgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fgz RCSB], [https://www.ebi.ac.uk/pdbsum/4fgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fgz ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoethanolamine_N-methyltransferase Phosphoethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.103 2.1.1.103] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fgz OCA], [http://pdbe.org/4fgz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fgz RCSB], [http://www.ebi.ac.uk/pdbsum/4fgz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fgz ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q6T755_PLAFA Q6T755_PLAFA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Phosphoethanolamine N-methyltransferase]]
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[[Category: Large Structures]]
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[[Category: Plafa]]
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[[Category: Plasmodium falciparum]]
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[[Category: Alpert, T D]]
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[[Category: Alpert TD]]
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[[Category: Jez, J M]]
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[[Category: Jez JM]]
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[[Category: Lee, S G]]
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[[Category: Lee SG]]
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[[Category: Methylation]]
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[[Category: Sam binding]]
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[[Category: Sam-dependent methyltransferase]]
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[[Category: Transferase]]
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Revision as of 19:48, 19 October 2022

Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine

PDB ID 4fgz

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