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4iah

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==Crystal Structure of BAY 60-2770 bound C139A H-NOX domain with S-nitrosylated conserved C122==
==Crystal Structure of BAY 60-2770 bound C139A H-NOX domain with S-nitrosylated conserved C122==
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<StructureSection load='4iah' size='340' side='right' caption='[[4iah]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='4iah' size='340' side='right'caption='[[4iah]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4iah]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Anabaena_7120 Anabaena 7120]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IAH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IAH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4iah]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IAH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IAH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1DX:4-({(4-CARBOXYBUTYL)[2-(5-FLUORO-2-{[4-(TRIFLUOROMETHYL)BIPHENYL-4-YL]METHOXY}PHENYL)ETHYL]AMINO}METHYL)BENZOIC+ACID'>1DX</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1DX:4-({(4-CARBOXYBUTYL)[2-(5-FLUORO-2-{[4-(TRIFLUOROMETHYL)BIPHENYL-4-YL]METHOXY}PHENYL)ETHYL]AMINO}METHYL)BENZOIC+ACID'>1DX</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SNC:S-NITROSO-CYSTEINE'>SNC</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SNC:S-NITROSO-CYSTEINE'>SNC</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4iah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iah OCA], [https://pdbe.org/4iah PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4iah RCSB], [https://www.ebi.ac.uk/pdbsum/4iah PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4iah ProSAT]</span></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3l6j|3l6j]], [[2o09|2o09]], [[2o0c|2o0c]], [[2o0g|2o0g]], [[4iae|4iae]], [[4iam|4iam]]</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">alr2278 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=103690 Anabaena 7120])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanylate_cyclase Guanylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.2 4.6.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iah FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iah OCA], [http://pdbe.org/4iah PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4iah RCSB], [http://www.ebi.ac.uk/pdbsum/4iah PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4iah ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8YUQ7_NOSS1 Q8YUQ7_NOSS1]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anabaena 7120]]
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[[Category: Large Structures]]
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[[Category: Guanylate cyclase]]
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[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
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[[Category: Akker, F van den]]
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[[Category: Kumar V]]
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[[Category: Kumar, V]]
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[[Category: Van den Akker F]]
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[[Category: Bay 60-2770]]
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[[Category: Conserved c122]]
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[[Category: H-nox domain]]
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[[Category: Heme binding]]
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[[Category: Lyase]]
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[[Category: No binding]]
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[[Category: S-nitrosylation]]
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[[Category: Soluble guanylyl cyclase]]
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Revision as of 08:53, 9 November 2022

Crystal Structure of BAY 60-2770 bound C139A H-NOX domain with S-nitrosylated conserved C122

PDB ID 4iah

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