1nq3

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[[Image:1nq3.gif|left|200px]]
[[Image:1nq3.gif|left|200px]]
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{{Structure
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{{STRUCTURE_1nq3| PDB=1nq3 | SCENE= }}
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|RELATEDENTRY=[[1qd9|1QD9]], [[1qu9|1QU9]], [[1jd1|1JD1]], [[1j7h|1J7H]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nq3 OCA], [http://www.ebi.ac.uk/pdbsum/1nq3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nq3 RCSB]</span>
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'''Crystal structure of the mammalian tumor associated antigen UK114'''
'''Crystal structure of the mammalian tumor associated antigen UK114'''
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[[Category: Mistiniene, E.]]
[[Category: Mistiniene, E.]]
[[Category: Naktinis, V.]]
[[Category: Naktinis, V.]]
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[[Category: crystal structure]]
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[[Category: Crystal structure]]
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[[Category: trimer]]
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[[Category: Trimer]]
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[[Category: tumor associated antigen]]
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[[Category: Tumor associated antigen]]
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[[Category: uk114]]
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[[Category: Uk114]]
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[[Category: yer057c/yil051c/yjgf protein family]]
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[[Category: Yer057c/yil051c/yjgf protein family]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 02:50:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:33:57 2008''
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Revision as of 23:50, 2 May 2008

Template:STRUCTURE 1nq3

Crystal structure of the mammalian tumor associated antigen UK114


Overview

The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.

About this Structure

1NQ3 is a Single protein structure of sequence from Capra hircus. Full crystallographic information is available from OCA.

Reference

Structure and oligomeric state of the mammalian tumour-associated antigen UK114., Deriu D, Briand C, Mistiniene E, Naktinis V, Grutter MG, Acta Crystallogr D Biol Crystallogr. 2003 Sep;59(Pt 9):1676-8. Epub 2003, Aug 19. PMID:12925811 Page seeded by OCA on Sat May 3 02:50:36 2008

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