3tvt
From Proteopedia
(Difference between revisions)
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==Structural basis for Discs Large interaction with Pins== | ==Structural basis for Discs Large interaction with Pins== | ||
| - | <StructureSection load='3tvt' size='340' side='right' caption='[[3tvt]], [[Resolution|resolution]] 1.60Å' scene=''> | + | <StructureSection load='3tvt' size='340' side='right'caption='[[3tvt]], [[Resolution|resolution]] 1.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3tvt]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3tvt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TVT FirstGlance]. <br> |
| - | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dlg1, l(1)dlg1, CG1725 ([ | + | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dlg1, l(1)dlg1, CG1725 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME]), raps, pins, CG5692 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tvt OCA], [https://pdbe.org/3tvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tvt RCSB], [https://www.ebi.ac.uk/pdbsum/3tvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tvt ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [[ | + | [[https://www.uniprot.org/uniprot/DLG1_DROME DLG1_DROME]] During embryonic development, some isoforms are essential for proper neuronal differentiation and organization. Required for cell polarity; maintenance of apicobasal polarity. Plays a critical role at septate junctions in cellular growth control during larval development. The presence of a guanylate kinase domain suggests involvement in cellular adhesion as well as signal transduction to control cellular proliferation.<ref>PMID:10884224</ref> <ref>PMID:12657668</ref> <ref>PMID:1651169</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Drome]] | [[Category: Drome]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Doe, C Q]] | [[Category: Doe, C Q]] | ||
[[Category: Johnston, C A]] | [[Category: Johnston, C A]] | ||
Revision as of 05:47, 13 July 2022
Structural basis for Discs Large interaction with Pins
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