1nz8

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[[Image:1nz8.jpg|left|200px]]
[[Image:1nz8.jpg|left|200px]]
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{{Structure
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|PDB= 1nz8 |SIZE=350|CAPTION= <scene name='initialview01'>1nz8</scene>
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The line below this paragraph, containing "STRUCTURE_1nz8", creates the "Structure Box" on the page.
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|GENE= NusG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
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{{STRUCTURE_1nz8| PDB=1nz8 | SCENE= }}
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|RELATEDENTRY=[[1nz9|1NZ9]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nz8 OCA], [http://www.ebi.ac.uk/pdbsum/1nz8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1nz8 RCSB]</span>
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'''Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus'''
'''Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus'''
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[[Category: Yamasaki, K.]]
[[Category: Yamasaki, K.]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama, S.]]
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[[Category: antitermination]]
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[[Category: Antitermination]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: Rsgi]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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[[Category: termination]]
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[[Category: Termination]]
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[[Category: transcription elongation]]
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[[Category: Transcription elongation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:10:08 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:37:33 2008''
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Revision as of 00:10, 3 May 2008

Image:1nz8.jpg

Template:STRUCTURE 1nz8

Solution Structure of the N-utilisation substance G (NusG) N-terminal (NGN) domain from Thermus thermophilus


Overview

NusG is an essential bacterial protein modulator of transcriptional elongation and termination events, and interacts directly with RNA polymerase and Rho protein. Found also in Archaea, NusG shows stretches of sequence similarity to the eukaryotic transcription elongation factor Spt5. Herein, the three-dimensional solution structure of the bacterial NusG from Thermus thermophilus, which shows 43% amino acid sequence similarity to the Escherichia coli NusG, is described, and a survey of NusG and Spt5 amino acid sequences is presented. Although there is a clear evolutionary and functional relationship between these proteins, it is evident from the structural, sequence, and biochemical data that their binding specificities to both nucleic acids and other proteins differ.

About this Structure

1NZ8 is a Single protein structure of sequence from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structural and sequence comparisons arising from the solution structure of the transcription elongation factor NusG from Thermus thermophilus., Reay P, Yamasaki K, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S, Proteins. 2004 Jul 1;56(1):40-51. PMID:15162485 Page seeded by OCA on Sat May 3 03:10:08 2008

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