4r76

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{{Large structure}}
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==Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor==
==Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor==
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<StructureSection load='4r76' size='340' side='right' caption='[[4r76]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='4r76' size='340' side='right'caption='[[4r76]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4r76]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R76 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4r76]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Plafq Plafq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R76 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=R5X:3-AMINO-N-{(1R)-2-(HYDROXYAMINO)-2-OXO-1-[4-(1H-PYRAZOL-1-YL)PHENYL]ETHYL}BENZAMIDE'>R5X</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=R5X:3-AMINO-N-{(1R)-2-(HYDROXYAMINO)-2-OXO-1-[4-(1H-PYRAZOL-1-YL)PHENYL]ETHYL}BENZAMIDE'>R5X</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ebg|3ebg]], [[4r5v|4r5v]], [[4r5x|4r5x]], [[4r6t|4r6t]], [[4r5t|4r5t]], [[4r7m|4r7m]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ebg|3ebg]], [[4r5v|4r5v]], [[4r5x|4r5x]], [[4r6t|4r6t]], [[4r5t|4r5t]], [[4r7m|4r7m]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r76 OCA], [http://pdbe.org/4r76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r76 RCSB], [http://www.ebi.ac.uk/pdbsum/4r76 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r76 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r76 OCA], [http://pdbe.org/4r76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r76 RCSB], [http://www.ebi.ac.uk/pdbsum/4r76 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r76 ProSAT]</span></td></tr>
</table>
</table>
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{{Large structure}}
 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Aminopeptidase|Aminopeptidase]]
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
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[[Category: Plafq]]
[[Category: Drinkwater, N]]
[[Category: Drinkwater, N]]
[[Category: Mcgowan, S]]
[[Category: Mcgowan, S]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease]]
[[Category: Protease]]

Revision as of 10:03, 1 May 2019

Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor

PDB ID 4r76

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