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4q0n
From Proteopedia
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==Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand== | ==Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand== | ||
| - | <StructureSection load='4q0n' size='340' side='right' caption='[[4q0n]], [[Resolution|resolution]] 1.78Å' scene=''> | + | <StructureSection load='4q0n' size='340' side='right'caption='[[4q0n]], [[Resolution|resolution]] 1.78Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4q0n]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q0N FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[4q0n]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q0N OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q0N FirstGlance]. <br> |
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2XD:(2E)-1-(2-HYDROXYPHENYL)-3-(2,4,5,7-TETRAHYDRO-6H-PYRAZOLO[3,4-C]PYRIDIN-6-YL)PROP-2-EN-1-ONE'>2XD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=2XD:(2E)-1-(2-HYDROXYPHENYL)-3-(2,4,5,7-TETRAHYDRO-6H-PYRAZOLO[3,4-C]PYRIDIN-6-YL)PROP-2-EN-1-ONE'>2XD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q0o|4q0o]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q0o|4q0o]]</td></tr> | ||
| + | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAF180, PB1, PBRM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q0n OCA], [http://pdbe.org/4q0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q0n RCSB], [http://www.ebi.ac.uk/pdbsum/4q0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q0n ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q0n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q0n OCA], [http://pdbe.org/4q0n PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4q0n RCSB], [http://www.ebi.ac.uk/pdbsum/4q0n PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4q0n ProSAT]</span></td></tr> | ||
</table> | </table> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Human]] | ||
| + | [[Category: Large Structures]] | ||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C]] | [[Category: Bountra, C]] | ||
Revision as of 08:15, 17 April 2019
Crystal Structure of the fifth bromodomain of Human Poly-bromodomain containing protein 1 (PB1) in complex with a hydroxyphenyl-propenone ligand
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Categories: Human | Large Structures | Arrowsmith, C H | Bountra, C | Chaikuad, A | Delft, F von | Edwards, A M | Fedorov, O | Felletar, I | Filippakopoulos, P | Knapp, S | Martin, S | Monteiro, O | Picaud, S | Structural genomic | Yue, W | Baf180 | Brg1-associated factor 180 | Bromodomain | Chromatin regulator | Dna-binding | Nucleus | Pb1 | Pbrm1 | Polybromo 1 isoform 1 | Polybromo-1d | Sgc | Transcription | Transcription regulation
