1o7p

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:1o7p.gif|left|200px]]
[[Image:1o7p.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 1o7p |SIZE=350|CAPTION= <scene name='initialview01'>1o7p</scene>, resolution 1.95&Aring;
+
The line below this paragraph, containing "STRUCTURE_1o7p", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Fe+Binding+Site+For+Chain+A'>AC1</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=NDH:(1R,+2S)-CIS+1,2+DIHYDROXY-1,2-DIHYDRONAPHTHALENE'>NDH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Naphthalene_1,2-dioxygenase Naphthalene 1,2-dioxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.12.12 1.14.12.12] </span>
+
or leave the SCENE parameter empty for the default display.
-
|GENE=
+
-->
-
|DOMAIN=
+
{{STRUCTURE_1o7p| PDB=1o7p | SCENE= }}
-
|RELATEDENTRY=
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1o7p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1o7p OCA], [http://www.ebi.ac.uk/pdbsum/1o7p PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1o7p RCSB]</span>
+
-
}}
+
'''NAPHTHALENE 1,2-DIOXYGENASE, PRODUCT COMPLEX'''
'''NAPHTHALENE 1,2-DIOXYGENASE, PRODUCT COMPLEX'''
Line 32: Line 29:
[[Category: Parales, R E.]]
[[Category: Parales, R E.]]
[[Category: Ramaswamy, S.]]
[[Category: Ramaswamy, S.]]
-
[[Category: aromatic hydrocarbon catabolism oxidoreductase]]
+
[[Category: Aromatic hydrocarbon catabolism oxidoreductase]]
-
[[Category: enzyme-substrate complex]]
+
[[Category: Enzyme-substrate complex]]
-
[[Category: iron-sulfur]]
+
[[Category: Iron-sulfur]]
-
[[Category: non-heme iron dioxygenase]]
+
[[Category: Non-heme iron dioxygenase]]
-
[[Category: oxidoreductase]]
+
[[Category: Oxidoreductase]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 03:29:26 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:41:03 2008''
+

Revision as of 00:29, 3 May 2008

Image:1o7p.gif

Template:STRUCTURE 1o7p

NAPHTHALENE 1,2-DIOXYGENASE, PRODUCT COMPLEX


Overview

Binding of oxygen to iron is exploited in several biological and chemical processes. Although computational and spectroscopic results have suggested side-on binding, only end-on binding of oxygen to iron has been observed in crystal structures. We have determined structures of naphthalene dioxygenase that show a molecular oxygen species bound to the mononuclear iron in a side-on fashion. In a complex with substrate and dioxygen, the dioxygen molecule is lined up for an attack on the double bond of the aromatic substrate. The structures reported here provide the basis for a reaction mechanism and for the high stereospecificity of the reaction catalyzed by naphthalene dioxygenase.

About this Structure

1O7P is a Protein complex structure of sequences from Pseudomonas putida. Full crystallographic information is available from OCA.

Reference

Crystal structure of naphthalene dioxygenase: side-on binding of dioxygen to iron., Karlsson A, Parales JV, Parales RE, Gibson DT, Eklund H, Ramaswamy S, Science. 2003 Feb 14;299(5609):1039-42. PMID:12586937 Page seeded by OCA on Sat May 3 03:29:26 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1o7p"
Personal tools