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Ribozyme
From Proteopedia
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**[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR /> | **[[1l8v]], [[1gid]] – TtRZ P4-P6 domain<BR /> | ||
**[[1hr2]] - TtRZ P4-P6 domain (mutant) <BR /> | **[[1hr2]] - TtRZ P4-P6 domain (mutant) <BR /> | ||
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*Various ribozymes | *Various ribozymes | ||
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**[[4qjh]] – twister RZ – synthetic<br /> | **[[4qjh]] – twister RZ – synthetic<br /> | ||
**[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br /> | **[[4rge]], [[4rgf]] – twister RZ env22 – synthetic<br /> | ||
| - | **[[ | + | **[[5k7c]],[[5k7d]],[[5k7e]] - pistol RZ - synthetic <br/> |
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== References == | == References == | ||
<references/> | <references/> | ||
[[Category: Topic Page]] | [[Category: Topic Page]] | ||
Revision as of 17:20, 22 August 2016
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Ribozyme (RZ) is an RNA molecule which catalyzes a chemical reaction[1].
- Glucosamine-6-phosphate activated RZ (glmS RZ) is a RZ and a riboswitch which regulates genes in response to metabolites.
- Leadzyme is a small, artificially-made RZ which can cleave RNA in the presence of lead. For more details on leadzyme see Student Projects for UMass Chemistry 423 Spring 2012-10.
- Hairpin RZ and hammerhead RZ are named based on their shape[2].
- Group I intron catalyzes its own selfish splicing[3].
Articles in Proteopedia concerning ribozymes include:
- Azoarcus group I intron
- Kink-turn motif
- Ribosome
- The Large Ribosomal Subunit
- Hairpin Ribozyme
- Human CPEB3 ribozyme's P4 domain
To view automatically seeded indices concerning ribozymes, see:
- Ribozyme
- Catalytic RNA
- GlmS
- Hammerhead
- Hairpin
- Hepatitis delta virus
- Twister
- Twister sister
- Hatchet
- Pistol
- Group I intron
- Varkud satellite
3D Structures of Ribozymes
Updated on 22-August-2016
References
- ↑ Tang J, Breaker RR. Rational design of allosteric ribozymes. Chem Biol. 1997 Jun;4(6):453-9. PMID:9224568
- ↑ Amarzguioui M, Prydz H. Hammerhead ribozyme design and application. Cell Mol Life Sci. 1998 Nov;54(11):1175-202. PMID:9849614 doi:http://dx.doi.org/10.1007/s000180050247
- ↑ Cech TR. Self-splicing of group I introns. Annu Rev Biochem. 1990;59:543-68. PMID:2197983 doi:http://dx.doi.org/10.1146/annurev.bi.59.070190.002551
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